SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5mx4d_ (5mx4 D:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2125386Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 2125403Superfamily c.56.2: Purine and uridine phosphorylases [53167] (2 families) (S)
    complex architecture; contains mixed beta-sheet of 8 strands, order 23415867, strands 3, 6 & 7 are antiparallel to the rest; and barrel, closed; n=5, S=8
  5. 2126300Family c.56.2.0: automated matches [191488] (1 protein)
    not a true family
  6. 2126301Protein automated matches [190781] (41 species)
    not a true protein
  7. 2289378Species Helicobacter pylori [TaxId:1145110] [332679] (1 PDB entry)
  8. 2289379Domain d5mx4d_: 5mx4 D: [332680]
    automated match to d4m3na_
    complexed with hpa, po4

Details for d5mx4d_

PDB Entry: 5mx4 (more details), 2.31 Å

PDB Description: crystal structure of h. pylori purine nucleoside phosphorylase from clinical isolate hppnp-1
PDB Compounds: (D:) Purine nucleoside phosphorylase deoD-type

SCOPe Domain Sequences for d5mx4d_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5mx4d_ c.56.2.0 (D:) automated matches {Helicobacter pylori [TaxId: 1145110]}
mtphinakigdfypqcllcgdplrvsyiakkflqdakeitnvrnmlgfsgkykgkgislm
ghgmgiasctiyvteliktyqvkellrigtcgaispkvglkdiimatgastdsktnrvrf
lnhdlsatpdfelslrayqtakrlgidlkignvfssdffysfethafdlmaqynhlaiem
eaaglyatamelnakalclcsvsdhlitkealspkeriesfdnmiilalemms

SCOPe Domain Coordinates for d5mx4d_:

Click to download the PDB-style file with coordinates for d5mx4d_.
(The format of our PDB-style files is described here.)

Timeline for d5mx4d_:

  • d5mx4d_ appears in periodic updates to SCOPe 2.06 starting on 2017-04-06