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Lineage for d5izcc_ (5izc C:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2090553Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2090925Protein Dihydropteridin reductase (pteridine reductase) [51769] (7 species)
  7. 2090996Species Trypanosoma brucei [TaxId:5702] [226783] (15 PDB entries)
  8. 2289304Domain d5izcc_: 5izc C: [332605]
    automated match to d3bmob_
    complexed with 6f4, act, gol, nap

Details for d5izcc_

PDB Entry: 5izc (more details), 1.92 Å

PDB Description: trypanosoma brucei ptr1 in complex with inhibitor f032
PDB Compounds: (C:) pteridine reductase

SCOPe Domain Sequences for d5izcc_:

Sequence, based on SEQRES records: (download)

>d5izcc_ c.2.1.2 (C:) Dihydropteridin reductase (pteridine reductase) {Trypanosoma brucei [TaxId: 5702]}
meapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcq
adltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvqgdhednsngktvetqv
aeligtnaiapflltmsfaqrqkgtnpnctssnlsivnlcdamvdqpcmafslynmgkha
lvgltqsaalelapygirvngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiada
viflvsgsaqyitgsiikvdgglslvha

Sequence, based on observed residues (ATOM records): (download)

>d5izcc_ c.2.1.2 (C:) Dihydropteridin reductase (pteridine reductase) {Trypanosoma brucei [TaxId: 5702]}
meapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcq
adltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvktvetqvaeligtnaia
pflltmsfaqrqsnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygirv
ngvapgvsllpdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvdgglslvh
a

SCOPe Domain Coordinates for d5izcc_:

Click to download the PDB-style file with coordinates for d5izcc_.
(The format of our PDB-style files is described here.)

Timeline for d5izcc_:

  • d5izcc_ appears in periodic updates to SCOPe 2.06 starting on 2017-04-05