Lineage for d5gnka_ (5gnk A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2195690Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 protein domains)
    members organized in the groups and subfamiles specified by the comments
  6. 2196778Protein EGF receptor tyrosine kinase, Erbb-1 [82795] (1 species)
    PTK group; EGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2196779Species Human (Homo sapiens) [TaxId:9606] [82796] (86 PDB entries)
    Uniprot P00533 702-1018
  8. 2289282Domain d5gnka_: 5gnk A: [332583]
    automated match to d4riyb_
    complexed with 80u, cl, edo, no3

Details for d5gnka_

PDB Entry: 5gnk (more details), 1.8 Å

PDB Description: crystal structure of egfr 696-988 t790m in complex with lxx-6-34
PDB Compounds: (A:) Epidermal growth factor receptor

SCOPe Domain Sequences for d5gnka_:

Sequence, based on SEQRES records: (download)

>d5gnka_ d.144.1.7 (A:) EGF receptor tyrosine kinase, Erbb-1 {Human (Homo sapiens) [TaxId: 9606]}
eapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspkan
keildeayvmasvdnphvcrllgicltstvqlimqlmpfgclldyvrehkdnigsqylln
wcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggkv
pikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqp
pictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgde

Sequence, based on observed residues (ATOM records): (download)

>d5gnka_ d.144.1.7 (A:) EGF receptor tyrosine kinase, Erbb-1 {Human (Homo sapiens) [TaxId: 9606]}
eapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspkan
keildeayvmasvdnphvcrllgicltstvqlimqlmpfgclldyvrehkdnigsqylln
wcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgvpikwmalesilh
riythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqppictidvymimv
kcwmidadsrpkfreliiefskmardpqrylviqgde

SCOPe Domain Coordinates for d5gnka_:

Click to download the PDB-style file with coordinates for d5gnka_.
(The format of our PDB-style files is described here.)

Timeline for d5gnka_:

  • d5gnka_ appears in periodic updates to SCOPe 2.06 starting on 2017-04-05