SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5j3la2 (5j3l A:95-214)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2008141Fold a.121: Tetracyclin repressor-like, C-terminal domain [48497] (1 superfamily)
    multihelical; interlocked (homo)dimer
  4. 2008142Superfamily a.121.1: Tetracyclin repressor-like, C-terminal domain [48498] (2 families) (S)
  5. 2008143Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain [48499] (35 protein domains)
  6. 2008150Protein Ethr repressor [109978] (2 species)
  7. 2008151Species Mycobacterium tuberculosis [TaxId:1773] [109979] (22 PDB entries)
    Uniprot P96222 22-215
  8. 2289095Domain d5j3la2: 5j3l A:95-214 [332396]
    Other proteins in same PDB: d5j3la1
    automated match to d1t56a2
    complexed with 6fr

Details for d5j3la2

PDB Entry: 5j3l (more details), 1.66 Å

PDB Description: structure of transcriptional regulatory repressor protein - ethr from mycobacterium tuberculosis in complex with 1-((2-cyclopentylethyl) sulfonyl)pyrrolidine at 1.66a resolution
PDB Compounds: (A:) HTH-type transcriptional regulator EthR

SCOPe Domain Sequences for d5j3la2:

Sequence; same for both SEQRES and ATOM records: (download)

>d5j3la2 a.121.1.1 (A:95-214) Ethr repressor {Mycobacterium tuberculosis [TaxId: 1773]}
adtdrenmwrtginvffetfgshkavtragqaaratsvevaelwstfmqkwiaytaavid
aerdrgaaprtlpahelatalnlmnertlfasfageqpsvpearvldtlvhiwvtsiyge

SCOPe Domain Coordinates for d5j3la2:

Click to download the PDB-style file with coordinates for d5j3la2.
(The format of our PDB-style files is described here.)

Timeline for d5j3la2:

  • d5j3la2 appears in periodic updates to SCOPe 2.06 starting on 2017-03-30

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Domains from same chain:
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d5j3la1