SCOPe 2.06: Domain d5uqwa_: 5uqw A:

Lineage for d5uqwa_ (5uqw A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein automated matches [190047] (29 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186768] (179 PDB entries)

8. Domain d5uqwa_: 5uqw A: [332303]
   automated match to d4obea_
   complexed with gdp, mg; mutant

Details for d5uqwa_

PDB Entry: 5uqw, 1.5 Å

PDB Description: crystal structure of human kras g12v mutant in complex with gdp

PDB Compounds: (A:) GTPase KRas

SCOPe Domain Sequences for d5uqwa_:

Sequence; same for both SEQRES and ATOM records:

>d5uqwa_ c.37.1.8 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgavgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdl
psrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhke

Timeline for d5uqwa_:

• d5uqwa_ is new in SCOPe 2.06-stable
  
• d5uqwa_ appears in SCOPe 2.07
  
• d5uqwa_ appears in the current release, SCOPe 2.08