SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5usje1 (5usj E:1-166)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2110099Family c.37.1.8: G proteins [52592] (79 protein domains)
    core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest
  6. 2111131Protein automated matches [190047] (28 species)
    not a true protein
  7. 2111209Species Human (Homo sapiens) [TaxId:9606] [186768] (155 PDB entries)
  8. 2288996Domain d5usje1: 5usj E:1-166 [332297]
    Other proteins in same PDB: d5usja2, d5usjb2, d5usjc2, d5usjd2, d5usje2, d5usjf2
    automated match to d4obea_
    complexed with gnp, mg; mutant

Details for d5usje1

PDB Entry: 5usj (more details), 1.94 Å

PDB Description: crystal structure of human kras g12d mutant in complex with gdpnp
PDB Compounds: (E:) GTPase KRas

SCOPe Domain Sequences for d5usje1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5usje1 c.37.1.8 (E:1-166) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgadgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdl
psrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkh

SCOPe Domain Coordinates for d5usje1:

Click to download the PDB-style file with coordinates for d5usje1.
(The format of our PDB-style files is described here.)

Timeline for d5usje1:

  • d5usje1 appears in periodic updates to SCOPe 2.06 starting on 2017-03-23