SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5uzsc1 (5uzs C:1-481)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2080656Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families) (S)
    The phosphate moiety of substrate binds in the 'common' phosphate-binding site
  5. 2080703Family c.1.5.0: automated matches [227276] (1 protein)
    not a true family
  6. 2080704Protein automated matches [227084] (14 species)
    not a true protein
  7. 2080757Species Clostridium perfringens [TaxId:195103] [258287] (8 PDB entries)
  8. 2288926Domain d5uzsc1: 5uzs C:1-481 [332227]
    Other proteins in same PDB: d5uzsa2, d5uzsb2, d5uzsc2, d5uzsd2
    automated match to d4q33a_
    complexed with 8l4, edo, imp, k, mg, peg, pg4, pge

Details for d5uzsc1

PDB Entry: 5uzs (more details), 2.37 Å

PDB Description: crystal structure of inosine 5'-monophosphate dehydrogenase from clostridium perfringens complexed with imp and p200
PDB Compounds: (C:) inosine-5'-monophosphate dehydrogenase

SCOPe Domain Sequences for d5uzsc1:

Sequence, based on SEQRES records: (download)

>d5uzsc1 c.1.5.0 (C:1-481) automated matches {Clostridium perfringens [TaxId: 195103]}
marilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaia
mareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdviv
ldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsict
trivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifag
ceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykghla
dtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys

Sequence, based on observed residues (ATOM records): (download)

>d5uzsc1 c.1.5.0 (C:1-481) automated matches {Clostridium perfringens [TaxId: 195103]}
marilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaia
mareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdviv
ldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsict
trivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifag
ceeapgaieiyqgrsykvyrgmgslgamakfvpegvegriaykghladtiyqliggiksg
mgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys

SCOPe Domain Coordinates for d5uzsc1:

Click to download the PDB-style file with coordinates for d5uzsc1.
(The format of our PDB-style files is described here.)

Timeline for d5uzsc1:

  • d5uzsc1 appears in periodic updates to SCOPe 2.06 starting on 2017-03-23