SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5uvfc_ (5uvf C:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2199100Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2199101Protein automated matches [190417] (25 species)
    not a true protein
  7. 2199241Species Human (Homo sapiens) [TaxId:9606] [187294] (778 PDB entries)
  8. 2288865Domain d5uvfc_: 5uvf C: [332166]
    automated match to d3op5a_
    complexed with 7dz, cl, peg, po4

Details for d5uvfc_

PDB Entry: 5uvf (more details), 2 Å

PDB Description: crystal structure of the human vaccinia-related kinase bound to bi- d1870
PDB Compounds: (C:) Serine/threonine-protein kinase VRK1

SCOPe Domain Sequences for d5uvfc_:

Sequence, based on SEQRES records: (download)

>d5uvfc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
favgeiitdmaaaawkvglpigqggfgciyladmnssesvgsdapcvvkvepsdngplft
elkfyqraakpeqiqkwirtrklkylgvpkywgsglhdkngksyrfmimdrfgsdlqkiy
eanakrfsrktvlqlslrildileyiheheyvhgdikasnlllnyknpdqvylvdyglay
rycpegvhkayaadpkrchdgtieftsidahngvapsrrgdleilgycmiqwltghlpwe
dnlkdpkyvrdskiryreniaslmdkcfpaanapgeiakymetvklldytekplyenlrd
illqglkaigskddgkldl

Sequence, based on observed residues (ATOM records): (download)

>d5uvfc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
favgeiitdmaaaawkvglpigqciyladmndapcvvkvepsgplftelkfyqraakpeq
iqkwirtrklkylgvpkywgsglhsyrfmimdrfgsdlqkiyeanakrfsrktvlqlslr
ildileyiheheyvhgdikasnlllnyknpdqvylvdyglayrycpegvhkayaadpkrc
hdgtieftsidahngvapsrrgdleilgycmiqwltghlpwednlkdpkyvrdskiryre
niaslmdkcfpaanapgeiakymetvklldytekplyenlrdillqglkaigskddgkld
l

SCOPe Domain Coordinates for d5uvfc_:

Click to download the PDB-style file with coordinates for d5uvfc_.
(The format of our PDB-style files is described here.)

Timeline for d5uvfc_:

  • d5uvfc_ appears in periodic updates to SCOPe 2.06 starting on 2017-03-23