SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5uawb1 (5uaw B:1-164)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2094257Family c.2.1.0: automated matches [191313] (1 protein)
    not a true family
  6. 2094258Protein automated matches [190069] (226 species)
    not a true protein
  7. 2095073Species Human (Homo sapiens) [TaxId:9606] [186944] (46 PDB entries)
  8. 2288244Domain d5uawb1: 5uaw B:1-164 [331545]
    Other proteins in same PDB: d5uawa2, d5uawb2, d5uawb3, d5uawc2, d5uawd2, d5uawd3, d5uawe2, d5uawe3
    automated match to d2izza1
    complexed with so4

Details for d5uawb1

PDB Entry: 5uaw (more details), 1.85 Å

PDB Description: structure of apo human pycr-1 crystallized in space group p21212
PDB Compounds: (B:) Pyrroline-5-carboxylate reductase 1, mitochondrial

SCOPe Domain Sequences for d5uawb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5uawb1 c.2.1.0 (B:1-164) automated matches {Human (Homo sapiens) [TaxId: 9606]}
msvgfigagqlafalakgftaagvlaahkimasspdmdlatvsalrkmgvkltphnketv
qhsdvlflavkphiipfildeigadiedrhivvscaagvtissiekklsafrpaprvirc
mtntpvvvregatvyatgthaqvedgrlmeqllssvgfctevee

SCOPe Domain Coordinates for d5uawb1:

Click to download the PDB-style file with coordinates for d5uawb1.
(The format of our PDB-style files is described here.)

Timeline for d5uawb1:

  • d5uawb1 appears in periodic updates to SCOPe 2.06 starting on 2017-03-16