SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Species: Hepatitis c virus genotype 2a (isolate jfh-1) [TaxId: 356411]

  1. Root: SCOPe 2.06
  2. 2217451Class e: Multi-domain proteins (alpha and beta) [56572] (69 folds)
  3. 2220074Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 2220075Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 2220913Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 protein domains)
  6. 2220921Protein Viral RNA polymerase [56695] (18 species)
  7. 2288058Species Hepatitis c virus genotype 2a (isolate jfh-1) [TaxId:356411] [331359] (1 PDB entry)

PDB entry in Species: Hepatitis c virus genotype 2a (isolate jfh-1) [TaxId: 356411]:

  • Domain(s) for 5twm:
    • 2288059Domain d5twma_: 5twm A: [331360]
      automated match to d3q0za_
      protein/RNA complex; complexed with 7ng, pe5, pg4, so4

More info for Species Hepatitis c virus genotype 2a (isolate jfh-1) [TaxId:356411] from e.8.1.4 Viral RNA polymerase

Timeline for Species Hepatitis c virus genotype 2a (isolate jfh-1) [TaxId:356411] from e.8.1.4 Viral RNA polymerase:

  • Species Hepatitis c virus genotype 2a (isolate jfh-1) [TaxId:356411] from e.8.1.4 Viral RNA polymerase appears in periodic updates to SCOPe 2.06 starting on 2017-03-16