Lineage for d5ksxf_ (5ksx F:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2010547Fold a.128: Terpenoid synthases [48575] (1 superfamily)
    multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers
  4. 2010548Superfamily a.128.1: Terpenoid synthases [48576] (6 families) (S)
    duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J
  5. 2010549Family a.128.1.1: Isoprenyl diphosphate synthases [48577] (4 protein domains)
  6. 2010594Protein automated matches [190489] (5 species)
    not a true protein
  7. 2010595Species Human (Homo sapiens) [TaxId:9606] [187688] (78 PDB entries)
  8. 2287747Domain d5ksxf_: 5ksx F: [331048]
    automated match to d4demf_
    complexed with 7am, po4

Details for d5ksxf_

PDB Entry: 5ksx (more details), 2.65 Å

PDB Description: crystal structure of human fpps in complex with an allosteric inhibitor am-02-072
PDB Compounds: (F:) farnesyl pyrophosphate synthase

SCOPe Domain Sequences for d5ksxf_:

Sequence, based on SEQRES records: (download)

>d5ksxf_ a.128.1.1 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vyaqekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvvvaf
relveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvglda
indanlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvrf
tekryksivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyldl
fgdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeel
dlpavflqyeedsyshimalieqyaaplppavflglarkiykr

Sequence, based on observed residues (ATOM records): (download)

>d5ksxf_ a.128.1.1 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vyaqekqdfvqhfsqivrvlteghpeigdaiarlkevleynaiggkynrgltvvvafrel
veprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgldaind
anlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqnvdlvrftekr
yksivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyldlfgdp
svtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeeldlpa
vflqyeedsyshimalieqyaaplppavflglarkiykr

SCOPe Domain Coordinates for d5ksxf_:

Click to download the PDB-style file with coordinates for d5ksxf_.
(The format of our PDB-style files is described here.)

Timeline for d5ksxf_:

  • d5ksxf_ appears in periodic updates to SCOPe 2.06 starting on 2017-03-16