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Lineage for d5ka3a_ (5ka3 A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2116263Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2116264Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2116365Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 protein domains)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 2116409Protein Tyrosine phosphatase [52806] (7 species)
  7. 2116410Species Human (Homo sapiens), 1B [TaxId:9606] [52807] (127 PDB entries)
    Uniprot P18031 2-300 ! Uniprot P18031 1-298 ! Uniprot P18031 2-299
  8. 2287437Domain d5ka3a_: 5ka3 A: [330738]
    automated match to d4y14b_
    complexed with cl, gol, ota, trs; mutant

Details for d5ka3a_

PDB Entry: 5ka3 (more details), 2.14 Å

PDB Description: protein tyrosine phosphatase 1b yaya (y152a, y153a) mutant in complex with tcs401, closed state
PDB Compounds: (A:) tyrosine-protein phosphatase non-receptor type 1

SCOPe Domain Sequences for d5ka3a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5ka3a_ c.45.1.2 (A:) Tyrosine phosphatase {Human (Homo sapiens), 1B [TaxId: 9606]}
emekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklhq
edndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkc
aqywpqkeekemifedtnlkltlisediksaatvrqlelenlttqetreilhfhyttwpd
fgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkdp
ssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvqdqwkelsh

SCOPe Domain Coordinates for d5ka3a_:

Click to download the PDB-style file with coordinates for d5ka3a_.
(The format of our PDB-style files is described here.)

Timeline for d5ka3a_:

  • d5ka3a_ appears in periodic updates to SCOPe 2.06 starting on 2017-03-08