SCOPe 2.06: Domain d5uqhh1: 5uqh H:1-481

Lineage for d5uqhh1 (5uqh H:1-481)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.0: automated matches [227276] (1 protein)
   not a true family

6. Protein automated matches [227084] (14 species)
   not a true protein

7. Species Campylobacter jejuni [TaxId:398000] [330482] (4 PDB entries)

8. Domain d5uqhh1: 5uqh H:1-481 [330612]
   Other proteins in same PDB: d5uqha2, d5uqhb2, d5uqhc2, d5uqhd2, d5uqhe2, d5uqhf2, d5uqhg2, d5uqhh2
   automated match to d4mz8b_
   complexed with 8l1, edo, imp, ipa, k

Details for d5uqhh1

PDB Entry: 5uqh, 2.2 Å

PDB Description: crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from campylobacter jejuni in the complex with inhibitor p182

PDB Compounds: (H:) Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase

SCOPe Domain Sequences for d5uqhh1:

Sequence, based on SEQRES records:

>d5uqhh1 c.1.5.0 (H:1-481) automated matches {Campylobacter jejuni [TaxId: 398000]}
mkivkraltfedvllrpgysevlpkevkihtkltknitlnmplisaamdtvtehraaimm
arlgglgvihknmdiasqvrevkrvkksesggikdlkkrkeypdankdnfgrlrvgaaig
vgqmdrvdalveagvdvvvldsahghskgiidtvkaikakypnldliagniataaaakal
ceagvdavkvgigpgsicttrivsgvgvpqisaidecveeankfgvpviadggikysgdi
akalavgassvmigsllagtdespgelftyqgrqyksyrgmgslgamqkgssdryfqqgt
aqdklvpegiegrvpyvgsirsvvhqllgglrssmgyvgakdiedfqkraefveittagl
keshvhdvtitheapnyk

Sequence, based on observed residues (ATOM records):

>d5uqhh1 c.1.5.0 (H:1-481) automated matches {Campylobacter jejuni [TaxId: 398000]}
mkivkraltfedvllrpgysevlpkevkihtkltknitlnmplisaamdtvtehraaimm
arlgglgvihknmdiasqvrevkrvkksekrkeypdankdnfgrlrvgaaigvgqmdrvd
alveagvdvvvldsahghskgiidtvkaikakypnldliagniataaaakalceagvdav
kvgigpgsicttrivsgvgvpqisaidecveeankfgvpviadggikysgdiakalavga
ssvmigsllagtdespgelftyqgrqyksyrgmgslgamqklvpegiegrvpyvgsirsv
vhqllgglrssmgyvgakdiedfqkraefveittaglkeshvhdvtitheapnyk

Timeline for d5uqhh1:

• d5uqhh1 is new in SCOPe 2.06-stable
  
• d5uqhh1 appears in SCOPe 2.07
  
• d5uqhh1 appears in the current release, SCOPe 2.08