SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5tx2b_ (5tx2 B:)

  1. Root: SCOPe 2.06
  2. 2229111Class g: Small proteins [56992] (94 folds)
  3. 2232568Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
    disulfide-rich fold; common core is all-beta
  4. 2232569Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families) (S)
  5. 2232656Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 protein domains)
  6. 2232729Protein TGF-beta2 [57510] (2 species)
  7. 2287150Species Mus musculus [TaxId:10090] [330451] (2 PDB entries)
  8. 2287227Domain d5tx2b_: 5tx2 B: [330528]
    automated match to d2tgia_
    mutant

Details for d5tx2b_

PDB Entry: 5tx2 (more details), 1.82 Å

PDB Description: miniature tgf-beta2 3-mutant monomer
PDB Compounds: (B:) Transforming growth factor beta-2

SCOPe Domain Sequences for d5tx2b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5tx2b_ g.17.1.2 (B:) TGF-beta2 {Mus musculus [TaxId: 10090]}
aldaaycfrnvqdncclrplyidfkrdlgwkwihepkgynanfcagacpyraskspscvs
qdlepltilyyigntpkieqlsnmivksckcs

SCOPe Domain Coordinates for d5tx2b_:

Click to download the PDB-style file with coordinates for d5tx2b_.
(The format of our PDB-style files is described here.)

Timeline for d5tx2b_:

  • d5tx2b_ appears in periodic updates to SCOPe 2.06 starting on 2017-03-02

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d5tx2a_