Lineage for d5tx4b_ (5tx4 B:)

  1. Root: SCOPe 2.07
  2. 2581248Class g: Small proteins [56992] (98 folds)
  3. 2584898Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
    disulfide-rich fold; common core is all-beta
  4. 2584899Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families) (S)
  5. 2584990Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 protein domains)
  6. 2585063Protein TGF-beta2 [57510] (2 species)
  7. 2585064Species Human (Homo sapiens) [TaxId:9606] [57511] (4 PDB entries)
  8. 2585067Domain d5tx4b_: 5tx4 B: [330453]
    Other proteins in same PDB: d5tx4a_
    automated match to d2tgia_

Details for d5tx4b_

PDB Entry: 5tx4 (more details), 1.88 Å

PDB Description: derivative of mouse tgf-beta2, with a deletion of residues 52-71 and k25r, r26k, l51r, a74k, c77s, l89v, i92v, k94r t95k, i98v single amino acid substitutions, bound to human tgf-beta type ii receptor ectodomain residues 15-130
PDB Compounds: (B:) Transforming growth factor beta-2

SCOPe Domain Sequences for d5tx4b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5tx4b_ g.17.1.2 (B:) TGF-beta2 {Human (Homo sapiens) [TaxId: 9606]}
aldaaycfrnvqdncclrplyidfrkdlgwkwihepkgynanfcagacpyraskspscvs
qdlepltivyyvgrkpkveqlsnmivksckcs

SCOPe Domain Coordinates for d5tx4b_:

Click to download the PDB-style file with coordinates for d5tx4b_.
(The format of our PDB-style files is described here.)

Timeline for d5tx4b_:

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d5tx4a_