SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Species: Mus musculus [TaxId: 10090]

  1. Root: SCOPe 2.06
  2. 2229111Class g: Small proteins [56992] (94 folds)
  3. 2232568Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
    disulfide-rich fold; common core is all-beta
  4. 2232569Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families) (S)
  5. 2232656Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 protein domains)
  6. 2232729Protein TGF-beta2 [57510] (2 species)
  7. 2287150Species Mus musculus [TaxId:10090] [330451] (2 PDB entries)

PDB entries in Species: Mus musculus [TaxId: 10090]:

  1. Domain(s) for 5tx2:
    1. 2287213Domain d5tx2a_: 5tx2 A: [330514]
      automated match to d2tgia_
      mutant
    2. 2287227Domain d5tx2b_: 5tx2 B: [330528]
      automated match to d2tgia_
      mutant
  2. Domain(s) for 5tx6:
    1. 2287151Domain d5tx6b_: 5tx6 B: [330452]
      automated match to d2tgia_
      complexed with ca; mutant
    2. 2287210Domain d5tx6a_: 5tx6 A: [330511]
      automated match to d2tgia_
      complexed with ca; mutant
    3. 2287253Domain d5tx6c_: 5tx6 C: [330554]
      automated match to d2tgia_
      complexed with ca; mutant

More info for Species Mus musculus [TaxId:10090] from g.17.1.2 TGF-beta2

Timeline for Species Mus musculus [TaxId:10090] from g.17.1.2 TGF-beta2:

  • Species Mus musculus [TaxId:10090] from g.17.1.2 TGF-beta2 appears in periodic updates to SCOPe 2.06 starting on 2017-03-02