SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5k00a_ (5k00 A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2199100Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2199101Protein automated matches [190417] (25 species)
    not a true protein
  7. 2199241Species Human (Homo sapiens) [TaxId:9606] [187294] (778 PDB entries)
  8. 2287081Domain d5k00a_: 5k00 A: [330382]
    automated match to d1zmua_
    complexed with 6pv

Details for d5k00a_

PDB Entry: 5k00 (more details), 1.77 Å

PDB Description: melk in complex with nvs-melk5
PDB Compounds: (A:) maternal embryonic leucine zipper kinase

SCOPe Domain Sequences for d5k00a_:

Sequence, based on SEQRES records: (download)

>d5k00a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mdydellkyyelhetigtggfakvklachiltgemvaikimdkntlgsdlprikteieal
knlrhqhicqlyhvletankifmvleycpggelfdyiisqdrlseeetrvvfrqivsava
yvhsqgyahrdlkpenllfdeyhklklidfglcakpkgnkdyhlqtccgslayaapeliq
gksylgseadvwsmgillyvlmcgflpfdddnvmalykkimrgkydvpkwlspssilllq
qmlqvdpkkrismknllnhpwimqdynypvewqsknpfihldddcvtelsvhhrnnrqtm
edlislwqydhltatyllllakkarg

Sequence, based on observed residues (ATOM records): (download)

>d5k00a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mdydellkyyelhetigtgakvklachiltgemvaikimdkntlgsdlprikteiealkn
lrhqhicqlyhvletankifmvleycpggelfdyiisqdrlseeetrvvfrqivsavayv
hsqgyahrdlkpenllfdeyhklklidfglcakpslayaapeliqgksylgseadvwsmg
illyvlmcgflpfdddnvmalykkimrgkydvpkwlspssilllqqmlqvdpkkrismkn
llnhpwimqdynypvewqsknpfihldddcvtelsvhhrnnrqtmedlislwqydhltat
yllllakkarg

SCOPe Domain Coordinates for d5k00a_:

Click to download the PDB-style file with coordinates for d5k00a_.
(The format of our PDB-style files is described here.)

Timeline for d5k00a_:

  • d5k00a_ appears in periodic updates to SCOPe 2.06 starting on 2017-03-01