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Lineage for d5uhnb_ (5uhn B:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2195690Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 protein domains)
    members organized in the groups and subfamiles specified by the comments
  6. 2198144Protein automated matches [190091] (14 species)
    not a true protein
  7. 2198237Species Human (Homo sapiens) [TaxId:9606] [188447] (583 PDB entries)
  8. 2286966Domain d5uhnb_: 5uhn B: [330267]
    automated match to d4v04b_
    complexed with acp, mg, so4; mutant

Details for d5uhnb_

PDB Entry: 5uhn (more details), 2.91 Å

PDB Description: crystal structure of the tyrosine kinase domain of fgf receptor 2 harboring a n549h/e565a double gain-of-function mutation
PDB Compounds: (B:) Fibroblast growth factor receptor 2

SCOPe Domain Sequences for d5uhnb_:

Sequence, based on SEQRES records: (download)

>d5uhnb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pedpkwefprdkltlgkplgegafgqvvmaeavgidkdkpkeavtvavkmlkddatekdl
sdlvsememmkmigkhkniihllgactqdgplyvivayaskgnlreylrarrppgmeysy
dinrvpeeqmtfkdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfgla
rdinnidyykkttngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypgip
veelfkllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlt

Sequence, based on observed residues (ATOM records): (download)

>d5uhnb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pedpkwefprdkltlgkplgegafgqvvmaeavgidkdkpkeavtvavkmlkddatekdl
sdlvsememmkmigkhkniihllgactqdgplyvivayaskgnlreylrarrqmtfkdlv
sctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfglardigrlpvkwmapeal
fdrvythqsdvwsfgvlmweiftlggspypgipveelfkllkeghrmdkpanctnelymm
mrdcwhavpsqrptfkqlvedldriltlt

SCOPe Domain Coordinates for d5uhnb_:

Click to download the PDB-style file with coordinates for d5uhnb_.
(The format of our PDB-style files is described here.)

Timeline for d5uhnb_:

  • d5uhnb_ appears in periodic updates to SCOPe 2.06 starting on 2017-02-23