SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5uq0b_ (5uq0 B:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2195690Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 protein domains)
    members organized in the groups and subfamiles specified by the comments
  6. 2198144Protein automated matches [190091] (14 species)
    not a true protein
  7. 2198237Species Human (Homo sapiens) [TaxId:9606] [188447] (583 PDB entries)
  8. 2286949Domain d5uq0b_: 5uq0 B: [330250]
    automated match to d5a46b_
    complexed with wp1

Details for d5uq0b_

PDB Entry: 5uq0 (more details), 2.3 Å

PDB Description: fgfr1 kinase domain complex with fragment 2,2-dimethyl-2,3- dihydrobenzofuran-7-carboxamide
PDB Compounds: (B:) fibroblast growth factor receptor 1

SCOPe Domain Sequences for d5uq0b_:

Sequence, based on SEQRES records: (download)

>d5uq0b_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdate
kdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgle
ysynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadf
glardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspyp
gvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivalts

Sequence, based on observed residues (ATOM records): (download)

>d5uq0b_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yelpedprwelprdrlvlgkplgegqvvlaeaiglrvtkvavkmlksdatekdlsdlise
memmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrqlsskdlvscayqv
argmeylaskkcihrdlaarnvlvtednvmkiadfgllpvkwmapealriythqsdvwsf
gvllweiftlggspypgvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrpt
fkqlvedldrivalts

SCOPe Domain Coordinates for d5uq0b_:

Click to download the PDB-style file with coordinates for d5uq0b_.
(The format of our PDB-style files is described here.)

Timeline for d5uq0b_:

  • d5uq0b_ appears in periodic updates to SCOPe 2.06 starting on 2017-02-23