Lineage for d5umea_ (5ume A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2826025Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2840637Superfamily c.1.23: FAD-linked oxidoreductase [51730] (3 families) (S)
    distinct cofactor-binding mode from both FMN- and NAD(P)-linked TIM-barrel oxidoreductases; families are related by a circular permutation
  5. 2840638Family c.1.23.1: Methylenetetrahydrofolate reductase [51731] (2 proteins)
    automatically mapped to Pfam PF02219
  6. 2840664Protein automated matches [193645] (4 species)
    not a true protein
  7. 2840676Species Haemophilus influenzae [TaxId:71421] [330195] (1 PDB entry)
  8. 2840677Domain d5umea_: 5ume A: [330248]
    Other proteins in same PDB: d5umee2
    automated match to d3fste_
    complexed with acy, edo, fad, fmt, so4

Details for d5umea_

PDB Entry: 5ume (more details), 2.7 Å

PDB Description: crystal structure of 5,10-methylenetetrahydrofolate reductase metf from haemophilus influenzae
PDB Compounds: (A:) 5,10-Methylenetetrahydrofolate reductase

SCOPe Domain Sequences for d5umea_:

Sequence, based on SEQRES records: (download)

>d5umea_ c.1.23.1 (A:) automated matches {Haemophilus influenzae [TaxId: 71421]}
yakeidtlnqhiadfnkkinvsfeffppknekmetllwdsihrlkvlkpkfvsvtygans
gerdrthgivkaikqetgleaaphltgidatpeelkqiardywdsgirrivalrgdepkg
yakkpfyasdlvellrsvadfdisvaaypevhpeaksaqadlinlkrkidaganhvitqf
ffdienylrfrdrcasigidteivpgilpvtnfkqlqkmasftnvkipawlvkaydgldn
dpttrnlvaasvamdmvkilsregvndfhfytlnrseltyaichmlgvrp

Sequence, based on observed residues (ATOM records): (download)

>d5umea_ c.1.23.1 (A:) automated matches {Haemophilus influenzae [TaxId: 71421]}
yakeidtlnqhiadfnkkinvsfeffppknekmetllwdsihrlkvlkpkfvsvtygans
gerdrthgivkaikqetgleaaphltgidatpeelkqiardywdsgirrivalrgdepkp
fyasdlvellrsvadfdisvaaypevhpeaksaqadlinlkrkidaganhvitqfffdie
nylrfrdrcasigidteivpgilpvtnfkqlqkmasftnvkipawlvkaydgldndpttr
nlvaasvamdmvkilsregvndfhfytlnrseltyaichmlgvrp

SCOPe Domain Coordinates for d5umea_:

Click to download the PDB-style file with coordinates for d5umea_.
(The format of our PDB-style files is described here.)

Timeline for d5umea_: