SCOPe 2.06: Domain d5ttva_: 5ttv A:

Lineage for d5ttva_ (5ttv A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d5ttva_: 5ttv A: [330213]
   automated match to d4e4ma_
   complexed with 7kx

Details for d5ttva_

PDB Entry: 5ttv, 1.93 Å

PDB Description: jak3 with covalent inhibitor 6

PDB Compounds: (A:) Tyrosine-protein kinase JAK3

SCOPe Domain Sequences for d5ttva_:

Sequence, based on SEQRES records:

>d5ttva_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ptifeerhlkyisqlgkgnfgsvelcrydplgdntgalvavkqlqhsgpdqqrdfqreiq
ilkalhsdfivkyrgvsygpgrqslrlvmeylpsgclrdflqrhrarldasrlllyssqi
ckgmeylgsrrcvhrdlaarnilveseahvkiadfglakllpldkdyyvvrepgqspifw
yapeslsdnifsrqsdvwsfgvvlyelftycdkscspsaeflrmmgcerdvpalsrllel
leegqrlpappacpaevhelmklcwapspqdrpsfsalgpqldmlws

Sequence, based on observed residues (ATOM records):

>d5ttva_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ptifeerhlkyisqlgkgnfgsvelcrydplgdntgalvavkqlgpdqqrdfqreiqilk
alhsdfivkyrgvsygpgrqslrlvmeylpsgclrdflqrhrarldasrlllyssqickg
meylgsrrcvhrdlaarnilveseahvkiadfglakllpldkdyyvvrepgqspifwyap
eslsdnifsrqsdvwsfgvvlyelftycdkscspsaeflrmmdvpalsrllelleegqrl
pappacpaevhelmklcwapspqdrpsfsalgpqldmlws

Timeline for d5ttva_:

• d5ttva_ is new in SCOPe 2.06-stable
  
• d5ttva_ appears in SCOPe 2.07
  
• d5ttva_ appears in the current release, SCOPe 2.08