SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5hn1b_ (5hn1 B:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2053108Fold b.42: beta-Trefoil [50352] (8 superfamilies)
    barrel, closed; n=6, S=12; and a hairpin triplet; meander
    duplication: has internal pseudo threefold symmetry
  4. 2053109Superfamily b.42.1: Cytokine [50353] (3 families) (S)
  5. 2053509Family b.42.1.0: automated matches [191477] (1 protein)
    not a true family
  6. 2053510Protein automated matches [190764] (2 species)
    not a true protein
  7. 2053518Species Human (Homo sapiens) [TaxId:9606] [187978] (6 PDB entries)
  8. 2286769Domain d5hn1b_: 5hn1 B: [330070]
    automated match to d4p0la_
    complexed with so4

Details for d5hn1b_

PDB Entry: 5hn1 (more details), 2.25 Å

PDB Description: crystal structure of interleukin-37
PDB Compounds: (B:) Interleukin-37

SCOPe Domain Sequences for d5hn1b_:

Sequence, based on SEQRES records: (download)

>d5hn1b_ b.42.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pkvknlnpkkfsihdqdhkvlvldsgnliavpdknyirpeiffalasslssasaekgspi
llgvskgefclycdkdkgqshpslqlkkeklmklaaqkesarrpfifyraqvgswnmles
aahpgwfictscncnepvgvtdkfenrkhiefsfqpv

Sequence, based on observed residues (ATOM records): (download)

>d5hn1b_ b.42.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pkvknlnpkkfsihdqdhkvlvldsgnliavpdknyirpeiffalasslssasaekgspi
llgvskgefclycdkshpslqlkkeklmklaaqkesarrpfifyraqgswnmlesaahpg
wfictscncnepvgvtdkfkhiefsfqpv

SCOPe Domain Coordinates for d5hn1b_:

Click to download the PDB-style file with coordinates for d5hn1b_.
(The format of our PDB-style files is described here.)

Timeline for d5hn1b_:

  • d5hn1b_ appears in periodic updates to SCOPe 2.06 starting on 2017-02-23