SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5h3qa_ (5h3q A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2199100Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2199101Protein automated matches [190417] (25 species)
    not a true protein
  7. 2199241Species Human (Homo sapiens) [TaxId:9606] [187294] (778 PDB entries)
  8. 2286690Domain d5h3qa_: 5h3q A: [329991]
    automated match to d3aoxa_
    complexed with 7hf, dtt, na

Details for d5h3qa_

PDB Entry: 5h3q (more details), 2.1 Å

PDB Description: crystal structure of trka kinase with ligand
PDB Compounds: (A:) high affinity nerve growth factor receptor

SCOPe Domain Sequences for d5h3qa_:

Sequence, based on SEQRES records: (download)

>d5h3qa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sglqghiienpqyfsdacvhhikrrdivlkwelgegafgkvflaechnllpeqdkmlvav
kalkeasesarqdfqreaelltmlqhqhivrffgvctegrpllmvfeymrhgdlnrflrs
hgpdakllaggedvapgplglgqllavasqvaagmvylaglhfvhrdlatrnclvgqglv
vkigdfgmsrdiystdyyrvggrtmlpirwmppesilyrkfttesdvwsfgvvlweifty
gkqpwyqlsnteaidcitqgrelerpracppevyaimrgcwqrepqqrhsikdvharlqa
laqappvyldvlg

Sequence, based on observed residues (ATOM records): (download)

>d5h3qa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sglqghiienpqyfsdacvhhikrrdivlkwelgegafgkvflaechnkmlvavkalkea
rqdfqreaelltmlqhqhivrffgvctegrpllmvfeymrhgdlnrflrshgpdakllag
gedvapgplglgqllavasqvaagmvylaglhfvhrdlatrnclvgqglvvkigdfgmsr
diystdyyrvggrtmlpirwmppesilyrkfttesdvwsfgvvlweiftygkqpwyqlsn
teaidcitqgrelerpracppevyaimrgcwqrepqqrhsikdvharlqalaqappvyld
vlg

SCOPe Domain Coordinates for d5h3qa_:

Click to download the PDB-style file with coordinates for d5h3qa_.
(The format of our PDB-style files is described here.)

Timeline for d5h3qa_:

  • d5h3qa_ appears in periodic updates to SCOPe 2.06 starting on 2017-02-22