SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5dbra_ (5dbr A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1994319Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 1994320Superfamily a.39.1: EF-hand [47473] (12 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 1994753Family a.39.1.5: Calmodulin-like [47502] (24 protein domains)
    Duplication: made with two pairs of EF-hands
  6. 1994810Protein Calmodulin [47516] (12 species)
  7. 1994893Species Human (Homo sapiens) [TaxId:9606] [47517] (84 PDB entries)
    Uniprot P02593
  8. 2286675Domain d5dbra_: 5dbr A: [329976]
    automated match to d3g43b_
    complexed with ca

Details for d5dbra_

PDB Entry: 5dbr (more details), 2.25 Å

PDB Description: ca2+ cam with human cardiac na+ channel (nav1.5) inactivation gate
PDB Compounds: (A:) calmodulin

SCOPe Domain Sequences for d5dbra_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5dbra_ a.39.1.5 (A:) Calmodulin {Human (Homo sapiens) [TaxId: 9606]}
lteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngti
dfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevde
mireadidgdgqvnyeefvqmmtak

SCOPe Domain Coordinates for d5dbra_:

Click to download the PDB-style file with coordinates for d5dbra_.
(The format of our PDB-style files is described here.)

Timeline for d5dbra_:

  • d5dbra_ appears in periodic updates to SCOPe 2.06 starting on 2017-02-22