SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5wt9l2 (5wt9 L:107-213)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2020524Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 protein domains)
  6. 2024392Protein automated matches [190374] (13 species)
    not a true protein
  7. 2024406Species Human (Homo sapiens) [TaxId:9606] [187221] (610 PDB entries)
  8. 2286623Domain d5wt9l2: 5wt9 L:107-213 [329924]
    Other proteins in same PDB: d5wt9g_, d5wt9l1
    automated match to d1dn0a2
    complexed with fuc, nag

Details for d5wt9l2

PDB Entry: 5wt9 (more details), 2.4 Å

PDB Description: complex structure of pd-1 and nivolumab-fab
PDB Compounds: (L:) Light Chain of Nivolumab

SCOPe Domain Sequences for d5wt9l2:

Sequence; same for both SEQRES and ATOM records: (download)

>d5wt9l2 b.1.1.2 (L:107-213) automated matches {Human (Homo sapiens) [TaxId: 9606]}
krtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteq
dskdstyslsstltlskadyekhkvyacevthqglsspvtksfnrge

SCOPe Domain Coordinates for d5wt9l2:

Click to download the PDB-style file with coordinates for d5wt9l2.
(The format of our PDB-style files is described here.)

Timeline for d5wt9l2:

  • d5wt9l2 appears in periodic updates to SCOPe 2.06 starting on 2017-02-16

View in 3D
Domains from same chain:
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d5wt9l1
View in 3D
Domains from other chains:
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d5wt9g_