SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5mt4a_ (5mt4 A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2057491Protein automated matches [190044] (14 species)
    not a true protein
  7. 2057530Species Human (Homo sapiens) [TaxId:9606] [187233] (142 PDB entries)
  8. 2286522Domain d5mt4a_: 5mt4 A: [329823]
    automated match to d1op8a_
    complexed with m7o

Details for d5mt4a_

PDB Entry: 5mt4 (more details), 1.65 Å

PDB Description: complement factor d in complex with a reversible benzoic acid based inhibitor
PDB Compounds: (A:) complement factor d

SCOPe Domain Sequences for d5mt4a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5mt4a_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ilggreaeaharpymasvqlngahlcggvlvaeqwvlsaahcledaadgkvqvllgahsl
sqpepskrlydvlravphpdsqpdtidhdllllqlsekatlgpavrplpwqrvdrdvapg
tlcdvagwgivnhagrrpdslqhvllpvldratcnrrthhdgaiterlmcaesnrrdsck
gdsggplvcggvlegvvtsgsrvcgnrkkpgiytrvasyaawidsvla

SCOPe Domain Coordinates for d5mt4a_:

Click to download the PDB-style file with coordinates for d5mt4a_.
(The format of our PDB-style files is described here.)

Timeline for d5mt4a_:

  • d5mt4a_ appears in periodic updates to SCOPe 2.06 starting on 2017-02-15