SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5lcha_ (5lch A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2205699Fold d.157: Metallo-hydrolase/oxidoreductase [56280] (1 superfamily)
    duplication of beta(4)-alpha-beta-alpha motif; 4 layers a/b/b/a; mixed beta-sheets
  4. 2205700Superfamily d.157.1: Metallo-hydrolase/oxidoreductase [56281] (15 families) (S)
  5. 2205701Family d.157.1.1: Zn metallo-beta-lactamase [56282] (2 protein domains)
  6. 2205847Protein automated matches [190079] (9 species)
    not a true protein
  7. 2205890Species Pseudomonas aeruginosa [TaxId:287] [189349] (28 PDB entries)
  8. 2286509Domain d5lcha_: 5lch A: [329810]
    automated match to d5a87b_
    complexed with 6tu, zn

Details for d5lcha_

PDB Entry: 5lch (more details), 1.94 Å

PDB Description: vim-2 metallo-beta-lactamase in complex with (s)-1-allyl-2-(3- methoxyphenyl)-3-oxoisoindoline-4-carboxylic acid (compound 42)
PDB Compounds: (A:) Metallo-beta-lactamase VIM-2

SCOPe Domain Sequences for d5lcha_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5lcha_ d.157.1.1 (A:) automated matches {Pseudomonas aeruginosa [TaxId: 287]}
yptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgaknt
aallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaevegneipt
hsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyelsrtsagnva
dadlaewptsieriqqhypeaqfvipghglpggldllkhttnvvkahtnr

SCOPe Domain Coordinates for d5lcha_:

Click to download the PDB-style file with coordinates for d5lcha_.
(The format of our PDB-style files is described here.)

Timeline for d5lcha_:

  • d5lcha_ appears in periodic updates to SCOPe 2.06 starting on 2017-02-15