SCOPe 2.08: Species: Human (Homo sapiens) [TaxId: 9606]

Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
consists of two intertwined (sub)domains related by pseudo dyad; duplication
3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
the constituent families form similar dimers
Family c.77.1.0: automated matches [191423] (1 protein)
not a true family
Protein automated matches [190603] (25 species)
not a true protein
Species Human (Homo sapiens) [TaxId:9606] [329721] (12 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

Domain(s) for 5gre:
1. Domain d5grea_: 5gre A: [329797]
  automated match to d3blxo_
  complexed with adp, cit, mg
2. Domain d5greb_: 5gre B: [329770]
  automated match to d3blxc_
  complexed with adp, cit, mg
Domain(s) for 5grf:
1. Domain d5grfa_: 5grf A: [329811]
  automated match to d3blxo_
  complexed with adp, cit, mg; mutant
2. Domain d5grfb_: 5grf B: [329729]
  automated match to d3blxc_
  complexed with adp, cit, mg; mutant
Domain(s) for 5grh:
1. Domain d5grha_: 5grh A: [329722]
  automated match to d3blxo_
  complexed with mg
2. Domain d5grhb_: 5grh B: [329776]
  automated match to d3blxc_
  complexed with mg
Domain(s) for 5gri:
1. Domain d5gria_: 5gri A: [329759]
  automated match to d3blxo_
  complexed with cit, mg
2. Domain d5grib_: 5gri B: [329750]
  automated match to d3blxc_
  complexed with cit, mg
Domain(s) for 5grl:
1. Domain d5grla_: 5grl A: [329778]
  automated match to d3blxo_
  complexed with adp, ict, mg
2. Domain d5grlb_: 5grl B: [329943]
  automated match to d3blxc_
  complexed with adp, ict, mg
Domain(s) for 5yvt:
1. Domain d5yvta_: 5yvt A: [348976]
  automated match to d3blxo_
  complexed with mg, nai
2. Domain d5yvtb_: 5yvt B: [348966]
  automated match to d3blxc_
  complexed with mg, nai
Domain(s) for 6kde:
1. Domain d6kdea_: 6kde A: [374636]
  Other proteins in same PDB: d6kdeb2, d6kded2
  automated match to d3blxc_
  complexed with ca
2. Domain d6kdeb1: 6kde B:15-340 [374677]
  Other proteins in same PDB: d6kdeb2, d6kded2
  automated match to d5grhb_
  complexed with ca
3. Domain d6kdec_: 6kde C: [374600]
  Other proteins in same PDB: d6kdeb2, d6kded2
  automated match to d3blxc_
  complexed with ca
4. Domain d6kded1: 6kde D:15-340 [374610]
  Other proteins in same PDB: d6kdeb2, d6kded2
  automated match to d5grhb_
  complexed with ca
Domain(s) for 6kdf:
1. Domain d6kdfa_: 6kdf A: [374711]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d3blxc_
2. Domain d6kdfb_: 6kdf B: [374648]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d3blxc_
3. Domain d6kdfc1: 6kdf C:14-340 [374822]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d5grhb_
4. Domain d6kdfd1: 6kdf D:14-340 [374945]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d5grhb_
5. Domain d6kdfe1: 6kdf E:1-337 [374841]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d3blxc_
6. Domain d6kdff1: 6kdf F:14-340 [374618]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d5grhb_
7. Domain d6kdfg_: 6kdf G: [374719]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d3blxc_
8. Domain d6kdfh1: 6kdf H:14-340 [374622]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d5grhb_
9. Domain d6kdfi_: 6kdf I: [374709]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d3blxc_
10. Domain d6kdfj1: 6kdf J:14-340 [374607]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d5grhb_
11. Domain d6kdfk_: 6kdf K: [374602]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d3blxc_
12. Domain d6kdfl1: 6kdf L:14-340 [374624]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d5grhb_
13. Domain d6kdfm_: 6kdf M: [374656]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d3blxc_
14. Domain d6kdfn1: 6kdf N:14-340 [374899]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d5grhb_
15. Domain d6kdfo_: 6kdf O: [374787]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d3blxc_
16. Domain d6kdfp1: 6kdf P:14-340 [374775]
  Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
  automated match to d5grhb_
Domain(s) for 6kdy:
1. Domain d6kdya_: 6kdy A: [374804]
  Other proteins in same PDB: d6kdyb2, d6kdyd2, d6kdyf2, d6kdyh2
  automated match to d3blxc_
  complexed with 2pe, nad, p6g, pe7, pg4
2. Domain d6kdyb1: 6kdy B:14-340 [374734]
  Other proteins in same PDB: d6kdyb2, d6kdyd2, d6kdyf2, d6kdyh2
  automated match to d5grhb_
  complexed with 2pe, nad, p6g, pe7, pg4
3. Domain d6kdyc_: 6kdy C: [374644]
  Other proteins in same PDB: d6kdyb2, d6kdyd2, d6kdyf2, d6kdyh2
  automated match to d3blxc_
  complexed with 2pe, nad, p6g, pe7, pg4
4. Domain d6kdyd1: 6kdy D:13-340 [374650]
  Other proteins in same PDB: d6kdyb2, d6kdyd2, d6kdyf2, d6kdyh2
  automated match to d5grhb_
  complexed with 2pe, nad, p6g, pe7, pg4
5. Domain d6kdye_: 6kdy E: [374596]
  Other proteins in same PDB: d6kdyb2, d6kdyd2, d6kdyf2, d6kdyh2
  automated match to d3blxc_
  complexed with 2pe, nad, p6g, pe7, pg4
6. Domain d6kdyf1: 6kdy F:14-340 [374773]
  Other proteins in same PDB: d6kdyb2, d6kdyd2, d6kdyf2, d6kdyh2
  automated match to d5grhb_
  complexed with 2pe, nad, p6g, pe7, pg4
7. Domain d6kdyg_: 6kdy G: [374597]
  Other proteins in same PDB: d6kdyb2, d6kdyd2, d6kdyf2, d6kdyh2
  automated match to d3blxc_
  complexed with 2pe, nad, p6g, pe7, pg4
8. Domain d6kdyh1: 6kdy H:14-340 [374704]
  Other proteins in same PDB: d6kdyb2, d6kdyd2, d6kdyf2, d6kdyh2
  automated match to d5grhb_
  complexed with 2pe, nad, p6g, pe7, pg4
Domain(s) for 6l57:
1. Domain d6l57a_: 6l57 A: [384652]
  automated match to d3blxa_
  complexed with atp, cit, mg
2. Domain d6l57b_: 6l57 B: [384657]
  automated match to d3blxc_
  complexed with atp, cit, mg
Domain(s) for 6l59:
1. Domain d6l59a_: 6l59 A: [384670]
  automated match to d3blxa_
  complexed with atp, cit, mg
2. Domain d6l59b_: 6l59 B: [384673]
  automated match to d3blxc_
  complexed with atp, cit, mg
Domain(s) for 8grg:
1. Domain d8grga_: 8grg A: [423513]
  automated match to d3blxo_
  mutant
2. Domain d8grgb_: 8grg B: [423522]
  automated match to d5grfb_
  mutant

More info for Species Human (Homo sapiens) [TaxId:9606] from c.77.1.0 automated matches

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.77.1.0 automated matches:

Species Human (Homo sapiens) [TaxId:9606] from c.77.1.0 automated matches first appeared in SCOPe 2.06, called Species Homo sapiens [TaxId:9606] from c.77.1.0 automated matches
Species Human (Homo sapiens) [TaxId:9606] from c.77.1.0 automated matches appears in SCOPe 2.07