SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5matc2 (5mat C:54-55)

  1. Root: SCOPe 2.06
  2. 2245868Class l: Artifacts [310555] (1 fold)
  3. 2245869Fold l.1: Tags [310573] (1 superfamily)
  4. 2245870Superfamily l.1.1: Tags [310607] (1 family) (S)
  5. 2245871Family l.1.1.1: Tags [310682] (2 protein domains)
  6. 2251949Protein N-terminal Tags [310894] (1 species)
  7. 2251950Species Synthetic [311501] (10528 PDB entries)
  8. 2286282Domain d5matc2: 5mat C:54-55 [329583]
    Other proteins in same PDB: d5mata1, d5matc1
    complexed with 7kj, p6g, pg4, so4, zn

Details for d5matc2

PDB Entry: 5mat (more details), 2.07 Å

PDB Description: structure of human sirtuin 2 in complex with a selective thienopyrimidinone based inhibitor
PDB Compounds: (C:) nad-dependent protein deacetylase sirtuin-2

SCOPe Domain Sequences for d5matc2:

Sequence; same for both SEQRES and ATOM records: (download)

>d5matc2 l.1.1.1 (C:54-55) N-terminal Tags {Synthetic}

SCOPe Domain Coordinates for d5matc2:

Click to download the PDB-style file with coordinates for d5matc2.
(The format of our PDB-style files is described here.)

Timeline for d5matc2:

  • d5matc2 appears in periodic updates to SCOPe 2.06 starting on 2017-02-09

View in 3D
Domains from same chain:
(mouse over for more information)