SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5lged2 (5lge D:415-415)

  1. Root: SCOPe 2.06
  2. 2245868Class l: Artifacts [310555] (1 fold)
  3. 2245869Fold l.1: Tags [310573] (1 superfamily)
  4. 2245870Superfamily l.1.1: Tags [310607] (1 family) (S)
  5. 2245871Family l.1.1.1: Tags [310682] (2 protein domains)
  6. 2245872Protein C-terminal Tags [310895] (1 species)
  7. 2245873Species Synthetic [311502] (4201 PDB entries)
  8. 2286211Domain d5lged2: 5lge D:415-415 [329512]
    Other proteins in same PDB: d5lgea1, d5lgeb1, d5lgec1, d5lged1
    complexed with 6vn, act, edo, nap; mutant

Details for d5lged2

PDB Entry: 5lge (more details), 2.7 Å

PDB Description: crystal structure of human idh1 mutant (r132h) in complex with nadp+ and an inhibitor related to bay 1436032
PDB Compounds: (D:) isocitrate dehydrogenase [nadp] cytoplasmic

SCOPe Domain Sequences for d5lged2:

Sequence; same for both SEQRES and ATOM records: (download)

>d5lged2 l.1.1.1 (D:415-415) C-terminal Tags {Synthetic}
s

SCOPe Domain Coordinates for d5lged2:

Click to download the PDB-style file with coordinates for d5lged2.
(The format of our PDB-style files is described here.)

Timeline for d5lged2:

  • d5lged2 appears in periodic updates to SCOPe 2.06 starting on 2017-02-09