SCOPe 2.08: Domain d5m18b3: 5m18 B:328-668

Lineage for d5m18b3 (5m18 B:328-668)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
   contains a cluster of helices and an alpha+beta sandwich

4. Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (4 families)

5. Family e.3.1.1: beta-Lactamase/D-ala carboxypeptidase [56602] (19 proteins)
   in the multi-domain class (e), this applies to domains with different numbers of (sub)domains than the most common domain
   

6. Protein Penicillin binding protein 2a (PBP2A), C-terminal domain [82838] (1 species)

7. Species Staphylococcus aureus [TaxId:1280] [82839] (10 PDB entries)
   Uniprot O54286 27-668

8. Domain d5m18b3: 5m18 B:328-668 [329503]
   Other proteins in same PDB: d5m18a1, d5m18a2, d5m18b1, d5m18b2
   automated match to d1vqqa3
   complexed with cd, mur

Details for d5m18b3

PDB Entry: 5m18, 1.98 Å

PDB Description: crystal structure of pbp2a from mrsa in the presence of cefepime ligand

PDB Compounds: (B:) Penicillin-binding protein 2

SCOPe Domain Sequences for d5m18b3:

Sequence, based on SEQRES records:

>d5m18b3 e.3.1.1 (B:328-668) Penicillin binding protein 2a (PBP2A), C-terminal domain {Staphylococcus aureus [TaxId: 1280]}
idakvqksiynnmkndygsgtaihpqtgellalvstpsydvypfmygmsneeynkltedk
kepllnkfqittspgstqkiltamiglnnktlddktsykidgkgwqkdkswggynvtrye
vvngnidlkqaiessdniffarvalelgskkfekgmkklgvgedipsdypfynaqisnkn
ldneilladsgygqgeilinpvqilsiysalenngninaphllkdtknkvwkkniisken
inlltdgmqqvvnkthkediyrsyanligksgtaelkmkqgetgrqigwfisydkdnpnm
mmainvkdvqdkgmasynakisgkvydelyengnkkydide

Sequence, based on observed residues (ATOM records):

>d5m18b3 e.3.1.1 (B:328-668) Penicillin binding protein 2a (PBP2A), C-terminal domain {Staphylococcus aureus [TaxId: 1280]}
idakvqksiynnmkndygsgtaihpqtgellalvstpsydvypfmygmsneeynkltedk
kepllnkfqittspgstqkiltamiglnnktlddktsykidgkgwqkdkswggynvtrye
vvngnidlkqaiessdniffarvalelgskkfekgmkklgvgedipsdypfynaqisnkn
ldneilladsgygqgeilinpvqilsiysalenngninaphllkdtknkvwkkniisken
inlltdgmqqvvnkthkediyrsyanligksgtaelgrqigwfisydkdnpnmmmainvk
dvqdkgmasynakisgkvydelyengnkkydide

Timeline for d5m18b3:

• d5m18b3 first appeared in SCOPe 2.06
  
• d5m18b3 appears in SCOPe 2.07