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Lineage for d5jq8a_ (5jq8 A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2195690Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 protein domains)
    members organized in the groups and subfamiles specified by the comments
  6. 2196228Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 2196229Species Human (Homo sapiens) [TaxId:9606] [88856] (372 PDB entries)
    Uniprot P24941
  8. 2286179Domain d5jq8a_: 5jq8 A: [329480]
    automated match to d1h00a_
    complexed with i73

Details for d5jq8a_

PDB Entry: 5jq8 (more details), 1.94 Å

PDB Description: crystal structure of cdk2 in complex with inhibitor icec0943
PDB Compounds: (A:) cyclin-dependent kinase 2

SCOPe Domain Sequences for d5jq8a_:

Sequence, based on SEQRES records: (download)

>d5jq8a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
nfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnhpn
ivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshr
vlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyyst
avdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpk
warqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records): (download)

>d5jq8a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
nfqkvekigegtygvvykarnkltgevvalkkipstaireisllkelnhpnivklldvih
tenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlkpq
nllintegaikladfglarafevvtlwyrapeillgckyystavdiwslgcifaemvtrr
alfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgr
sllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

SCOPe Domain Coordinates for d5jq8a_:

Click to download the PDB-style file with coordinates for d5jq8a_.
(The format of our PDB-style files is described here.)

Timeline for d5jq8a_:

  • d5jq8a_ appears in periodic updates to SCOPe 2.06 starting on 2017-02-08