SCOPe 2.08: Domain d5tqfl_: 5tqf L:

Lineage for d5tqfl_ (5tqf L:)

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (8 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein Coagulation factor VIIa [57201] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57202] (97 PDB entries)
   Uniprot P08709 108-202 ! Uniprot P08709 107-202

8. Domain d5tqfl_: 5tqf L: [329373]
   Other proteins in same PDB: d5tqfh_
   automated match to d1cvwl_
   complexed with 7kr, ca, gol, so4

Details for d5tqfl_

PDB Entry: 5tqf, 1.85 Å

PDB Description: factor viia in complex with the inhibitor (11r)-11-[(1- aminoisoquinolin-6-yl)amino]-16-(cyclopropylsulfonyl)-13-methyl-2,13- diazatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaene-3, 12-dione

PDB Compounds: (L:) Factor VIIa (Light Chain)

SCOPe Domain Sequences for d5tqfl_:

Sequence; same for both SEQRES and ATOM records:

>d5tqfl_ g.3.11.1 (L:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekr

Timeline for d5tqfl_:

• d5tqfl_ first appeared in SCOPe 2.06
  
• d5tqfl_ appears in SCOPe 2.07