Lineage for d5tqfh_ (5tqf H:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2056099Protein Coagulation factor VIIa [50550] (1 species)
  7. 2056100Species Human (Homo sapiens) [TaxId:9606] [50551] (88 PDB entries)
    Uniprot P08709 213-466 ! Uniprot P08709 213-446
  8. 2286043Domain d5tqfh_: 5tqf H: [329344]
    Other proteins in same PDB: d5tqfl_
    automated match to d1klih_
    complexed with 7kr, ca, gol, so4

Details for d5tqfh_

PDB Entry: 5tqf (more details), 1.85 Å

PDB Description: factor viia in complex with the inhibitor (11r)-11-[(1- aminoisoquinolin-6-yl)amino]-16-(cyclopropylsulfonyl)-13-methyl-2,13- diazatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaene-3, 12-dione
PDB Compounds: (H:) Factor VIIa (Heavy Chain)

SCOPe Domain Sequences for d5tqfh_:

Sequence, based on SEQRES records: (download)

>d5tqfh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Sequence, based on observed residues (ATOM records): (download)

>d5tqfh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkpniteymfcagysdgs
kdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrsepr
pgvllrapfp

SCOPe Domain Coordinates for d5tqfh_:

Click to download the PDB-style file with coordinates for d5tqfh_.
(The format of our PDB-style files is described here.)

Timeline for d5tqfh_:

  • d5tqfh_ appears in periodic updates to SCOPe 2.06 starting on 2017-02-02