Lineage for d5tqeh_ (5tqe H:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2056099Protein Coagulation factor VIIa [50550] (1 species)
  7. 2056100Species Human (Homo sapiens) [TaxId:9606] [50551] (88 PDB entries)
    Uniprot P08709 213-466 ! Uniprot P08709 213-446
  8. 2286012Domain d5tqeh_: 5tqe H: [329313]
    Other proteins in same PDB: d5tqel_
    automated match to d1klih_
    complexed with 7kq, ca, gol, so4

Details for d5tqeh_

PDB Entry: 5tqe (more details), 1.9 Å

PDB Description: factor viia in complex with the inhibitor (5r)-5-[(1-aminoisoquinolin- 6-yl)amino]-19-(cyclopropylsulfonyl)-3-methyl-13-oxa-3,15- diazatricyclo[14.3.1.1~6,10~]henicosa-1(20),6(21),7,9,16,18-hexaene- 4,14-dione
PDB Compounds: (H:) Factor VIIa (Heavy Chain)

SCOPe Domain Sequences for d5tqeh_:

Sequence, based on SEQRES records: (download)

>d5tqeh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Sequence, based on observed residues (ATOM records): (download)

>d5tqeh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkdspniteymfcagysd
gskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrse
prpgvllrapfp

SCOPe Domain Coordinates for d5tqeh_:

Click to download the PDB-style file with coordinates for d5tqeh_.
(The format of our PDB-style files is described here.)

Timeline for d5tqeh_:

  • d5tqeh_ appears in periodic updates to SCOPe 2.06 starting on 2017-02-02