Lineage for d5wrqa1 (5wrq A:662-796)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2321349Fold a.41: Domain of poly(ADP-ribose) polymerase [47586] (1 superfamily)
    core: 4 helices: bundle; unusual topology
  4. 2321350Superfamily a.41.1: Domain of poly(ADP-ribose) polymerase [47587] (2 families) (S)
    duplication: consists of 2 helix-loop-helix structural repeats
    automatically mapped to Pfam PF02877
  5. 2321375Family a.41.1.0: automated matches [227223] (1 protein)
    not a true family
  6. 2321376Protein automated matches [226964] (1 species)
    not a true protein
  7. 2321377Species Human (Homo sapiens) [TaxId:9606] [225405] (44 PDB entries)
  8. 2321445Domain d5wrqa1: 5wrq A:662-796 [329160]
    Other proteins in same PDB: d5wrqa2, d5wrqa3, d5wrqb2, d5wrqb3
    automated match to d4hhyd1
    complexed with 7tx

Details for d5wrqa1

PDB Entry: 5wrq (more details), 2.65 Å

PDB Description: structure of human parp1 catalytic domain bound to a quinazoline-2, 4(1h,3h)-dione inhibitor
PDB Compounds: (A:) Poly [ADP-ribose] polymerase 1

SCOPe Domain Sequences for d5wrqa1:

Sequence, based on SEQRES records: (download)

>d5wrqa1 a.41.1.0 (A:662-796) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavs
qgssdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrgg
sddsskdpidvnyek

Sequence, based on observed residues (ATOM records): (download)

>d5wrqa1 a.41.1.0 (A:662-796) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavs
qgsdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrggs
ddsskdpidvnyek

SCOPe Domain Coordinates for d5wrqa1:

Click to download the PDB-style file with coordinates for d5wrqa1.
(The format of our PDB-style files is described here.)

Timeline for d5wrqa1: