Lineage for d5m2bx_ (5m2b X:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2201124Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 2201125Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 2201309Family d.153.1.4: Proteasome subunits [56251] (4 protein domains)
  6. 2202517Protein Proteasome beta subunit (catalytic) [56252] (6 species)
  7. 2202526Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (174 PDB entries)
    The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
  8. 2285815Domain d5m2bx_: 5m2b X: [329116]
    Other proteins in same PDB: d5m2bb_, d5m2bc_, d5m2bd_, d5m2be_, d5m2bf_, d5m2bg_, d5m2bh_, d5m2bk_, d5m2bl_, d5m2bm_, d5m2bp_, d5m2bq_, d5m2br_, d5m2bs_, d5m2bt_, d5m2bu_, d5m2bv_, d5m2by_, d5m2bz_
    automated match to d1rypk_
    complexed with 7dx, cl, mg

Details for d5m2bx_

PDB Entry: 5m2b (more details), 2.7 Å

PDB Description: yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with thiazole based inhibitor ro19
PDB Compounds: (X:) Proteasome subunit beta type-4

SCOPe Domain Sequences for d5m2bx_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5m2bx_ d.153.1.4 (X:) Proteasome beta subunit (catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}

SCOPe Domain Coordinates for d5m2bx_:

Click to download the PDB-style file with coordinates for d5m2bx_.
(The format of our PDB-style files is described here.)

Timeline for d5m2bx_:

  • d5m2bx_ appears in periodic updates to SCOPe 2.06 starting on 2017-01-26