SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5huoc2 (5huo C:117-288)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2089241Superfamily c.1.17: Nicotinate/Quinolinate PRTase C-terminal domain-like [51690] (3 families) (S)
    incomplete beta/alpha barrel with parallel beta-sheet of 7 strands
  5. 2089313Family c.1.17.0: automated matches [227169] (1 protein)
    not a true family
  6. 2089314Protein automated matches [226879] (8 species)
    not a true protein
  7. 2285557Species Streptococcus pyogenes [TaxId:1115816] [328858] (1 PDB entry)
  8. 2285712Domain d5huoc2: 5huo C:117-288 [329013]
    Other proteins in same PDB: d5huoa1, d5huob1, d5huoc1, d5huoe1, d5huof1, d5huoh1
    automated match to d1x1oa2
    complexed with so4; mutant

Details for d5huoc2

PDB Entry: 5huo (more details), 2.8 Å

PDB Description: crystal structure of nadc deletion mutant in c2221 space group
PDB Compounds: (C:) Nicotinate-nucleotide diphosphorylase (Carboxylating)

SCOPe Domain Sequences for d5huoc2:

Sequence, based on SEQRES records: (download)

>d5huoc2 c.1.17.0 (C:117-288) automated matches {Streptococcus pyogenes [TaxId: 1115816]}
iasmtaayvealgddrikvfdtrkttpnlrlfekyavrvgggynhrfnlsdaimlkdnhi
aavgsvqkaiaqarayapfvkmveveveslaaaeeaaaagvdiimldnmsleqieqaitl
iagrsriecsgnidmttisrfrglaidyvssgslthsaksldfsmkgltyld

Sequence, based on observed residues (ATOM records): (download)

>d5huoc2 c.1.17.0 (C:117-288) automated matches {Streptococcus pyogenes [TaxId: 1115816]}
iasmtaayvealgddrikvfdtrkttpnlrlfekyavrvgggynhrfnlsdaimlkdnhi
asvqkaiaqarayapfvkmveveveslaaaeeaaaagvdiimldnmsleqieqaitliag
rsriecsgnidmttisrfrglaidyvssgslthsaksldfsmkgltyld

SCOPe Domain Coordinates for d5huoc2:

Click to download the PDB-style file with coordinates for d5huoc2.
(The format of our PDB-style files is described here.)

Timeline for d5huoc2:

  • d5huoc2 appears in periodic updates to SCOPe 2.06 starting on 2017-01-26