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Lineage for d5fucb_ (5fuc B:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991438Family a.26.1.1: Long-chain cytokines [47267] (10 protein domains)
  6. 1991516Protein automated matches [190263] (1 species)
    not a true protein
  7. 1991517Species Human (Homo sapiens) [TaxId:9606] [187052] (11 PDB entries)
  8. 2285667Domain d5fucb_: 5fuc B: [328968]
    Other proteins in same PDB: d5fuca2, d5fucc1, d5fucc2, d5fucd1, d5fucd2, d5fuce_, d5fucv_
    automated match to d4cnic_
    complexed with nag

Details for d5fucb_

PDB Entry: 5fuc (more details), 2.7 Å

PDB Description: biophysical and cellular characterisation of a junctional epitope antibody that locks il-6 and gp80 together in a stable complex: implications for new therapeutic strategies
PDB Compounds: (B:) interleukin-6

SCOPe Domain Sequences for d5fucb_:

Sequence, based on SEQRES records: (download)

>d5fucb_ a.26.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sseridkqiryildgisalrketcnksnmcesskealaennlnlpkmaekdgcfqsgfne
etclvkiitgllefevyleylqnrfesseeqaravqmstkvliqflqkkaknldaittpd
pttnaslltklqaqnqwlqdmtthlilrsfkeflqsslralrqm

Sequence, based on observed residues (ATOM records): (download)

>d5fucb_ a.26.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sseridkqiryildgisalrketcnksnmcesskealaennlnlpkmaekdgcfqsgfne
etclvkiitgllefevyleylqnrfesseeqaravqmstkvliqflqkkakittpdpttn
aslltklqaqnqwlqdmtthlilrsfkeflqsslralrqm

SCOPe Domain Coordinates for d5fucb_:

Click to download the PDB-style file with coordinates for d5fucb_.
(The format of our PDB-style files is described here.)

Timeline for d5fucb_:

  • d5fucb_ appears in periodic updates to SCOPe 2.06 starting on 2017-01-26