Lineage for d5j71a2 (5j71 A:187-392)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2537076Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
    8-stranded mixed beta-sheet; 2 layers: alpha/beta
  4. 2537077Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families) (S)
  5. 2537637Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain [69804] (3 protein domains)
  6. 2537655Protein Pyruvate dehydrogenase kinase [69807] (2 species)
  7. 2537656Species Human (Homo sapiens) [TaxId:9606] [160702] (16 PDB entries)
    Uniprot Q15120 177-301
  8. 2537661Domain d5j71a2: 5j71 A:187-392 [328924]
    Other proteins in same PDB: d5j71a1
    automated match to d1y8oa3
    complexed with p35, tla

Details for d5j71a2

PDB Entry: 5j71 (more details), 1.65 Å

PDB Description: crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor ps35
PDB Compounds: (A:) [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial

SCOPe Domain Sequences for d5j71a2:

Sequence, based on SEQRES records: (download)

>d5j71a2 d.122.1.4 (A:187-392) Pyruvate dehydrogenase kinase {Human (Homo sapiens) [TaxId: 9606]}
higsidpncnvsevvkdaydmakllcdkyymaspdleiqeinaanskqpihmvyvpshly
hmlfelfknamratveshesslilppikvmvalgeedlsikmsdrgggvplrkierlfsy
mystaptpqpgtggtplagfgyglpisrlyakyfqgdlqlfsmegfgtdaviylkalstd
sverlpvynksawrhyqtiqeagdwc

Sequence, based on observed residues (ATOM records): (download)

>d5j71a2 d.122.1.4 (A:187-392) Pyruvate dehydrogenase kinase {Human (Homo sapiens) [TaxId: 9606]}
higsidpncnvsevvkdaydmakllcdkyymaspdleiqeinaansqpihmvyvpshlyh
mlfelfknamratveshesslilppikvmvalgeedlsikmsdrgggvplrkierlfsym
gyglpisrlyakyfqgdlqlfsmegfgtdaviylkalstdsverlpvynksawrhydwc

SCOPe Domain Coordinates for d5j71a2:

Click to download the PDB-style file with coordinates for d5j71a2.
(The format of our PDB-style files is described here.)

Timeline for d5j71a2:

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Domains from same chain:
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d5j71a1