SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5hdea_ (5hde A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2116263Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2116264Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2116650Family c.45.1.0: automated matches [191381] (1 protein)
    not a true family
  6. 2116651Protein automated matches [190475] (8 species)
    not a true protein
  7. 2116663Species Human (Homo sapiens) [TaxId:9606] [187400] (110 PDB entries)
  8. 2285507Domain d5hdea_: 5hde A: [328808]
    automated match to d4j51a_
    complexed with po4

Details for d5hdea_

PDB Entry: 5hde (more details), 1.62 Å

PDB Description: crystal structure of ptpn12 catalytic domain
PDB Compounds: (A:) Tyrosine-protein phosphatase non-receptor type 12

SCOPe Domain Sequences for d5hdea_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5hdea_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eqveilrkfiqrvqamkspdhngednfardfmrlrrlstkyrtekiyptatgekeenvkk
nrykdilpfdhsrvkltlktpsqdsdyinanfikgvygpkayvatqgplantvidfwrmi
weynvviivmacrefemgrkkcerywplygedpitfapfkiscedeqartdyfirtllle
fqnesrrlyqfhyvnwpdhdvpssfdsildmislmrkyqehedvpicihcsagcgrtgai
caidytwnllkagkipeefnvfnliqemrtqrhsavqtkeqyelvhraiaqlfekqlqly

SCOPe Domain Coordinates for d5hdea_:

Click to download the PDB-style file with coordinates for d5hdea_.
(The format of our PDB-style files is described here.)

Timeline for d5hdea_:

  • d5hdea_ appears in periodic updates to SCOPe 2.06 starting on 2017-01-19