SCOPe 2.08: Domain d5m4ia_: 5m4i A:

Lineage for d5m4ia_ (5m4i A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Protein kinase CK2, alpha subunit [56142] (3 species)
   CMGC group; CK2 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [75559] (184 PDB entries)

8. Domain d5m4ia_: 5m4i A: [328714]
   automated match to d3juha_
   complexed with 7fc, cl

Details for d5m4ia_

PDB Entry: 5m4i, 2.22 Å

PDB Description: complex structure of human protein kinase ck2 catalytic subunit with the inhibitor 4'-carboxy-6,8-chloro-flavonol (flc21) crystallized under high-salt conditions

PDB Compounds: (A:) Casein kinase II subunit alpha

SCOPe Domain Sequences for d5m4ia_:

Sequence; same for both SEQRES and ATOM records:

>d5m4ia_ d.144.1.7 (A:) Protein kinase CK2, alpha subunit {Human (Homo sapiens) [TaxId: 9606]}
gpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitnn
ekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdfk
qlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaefy
hpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydql
vriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfld
kllrydhqsrltareamehpyfytvvkdqar

Timeline for d5m4ia_:

• d5m4ia_ first appeared in SCOPe 2.06
  
• d5m4ia_ appears in SCOPe 2.07