Lineage for d5mrda_ (5mrd A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2199100Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2199101Protein automated matches [190417] (25 species)
    not a true protein
  7. 2199241Species Human (Homo sapiens) [TaxId:9606] [187294] (842 PDB entries)
  8. 2285409Domain d5mrda_: 5mrd A: [328710]
    automated match to d4aw1a_
    complexed with atp, dms, dtt, s26

Details for d5mrda_

PDB Entry: 5mrd (more details), 1.41 Å

PDB Description: human pdk1-pkciota kinase chimera in complex with allosteric compound ps267 bound to the pif-pocket
PDB Compounds: (A:) 3-phosphoinositide-dependent protein kinase 1

SCOPe Domain Sequences for d5mrda_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5mrda_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
skrpedfkfgkilgegsfstvvlarelatsreyaikivekrhvnkenkipyvqrekdvms
rldhpffvklyfcfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsaley
lhgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvspellt
eksackssdlwalgciiyqlvaglppfragneglifakiikleydfpekffpkardlvek
llvldatkrlgceemegygplkahpffesvtwenlhqqtppklt

SCOPe Domain Coordinates for d5mrda_:

Click to download the PDB-style file with coordinates for d5mrda_.
(The format of our PDB-style files is described here.)

Timeline for d5mrda_:

  • d5mrda_ appears in periodic updates to SCOPe 2.06 starting on 2017-01-19