SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5ieza2 (5iez A:171-171)

  1. Root: SCOPe 2.06
  2. 2245868Class l: Artifacts [310555] (1 fold)
  3. 2245869Fold l.1: Tags [310573] (1 superfamily)
  4. 2245870Superfamily l.1.1: Tags [310607] (1 family) (S)
  5. 2245871Family l.1.1.1: Tags [310682] (2 protein domains)
  6. 2251949Protein N-terminal Tags [310894] (1 species)
  7. 2251950Species Synthetic [311501] (10430 PDB entries)
  8. 2285333Domain d5ieza2: 5iez A:171-171 [328634]
    Other proteins in same PDB: d5ieza1, d5iezb_, d5iezc_, d5iezd1
    complexed with 6al

Details for d5ieza2

PDB Entry: 5iez (more details), 2.6 Å

PDB Description: discovery of potent myeloid cell leukemia-1 (mcl-1) inhibitors using structure-based design
PDB Compounds: (A:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d5ieza2:

Sequence; same for both SEQRES and ATOM records: (download)

>d5ieza2 l.1.1.1 (A:171-171) N-terminal Tags {Synthetic}
d

SCOPe Domain Coordinates for d5ieza2:

Click to download the PDB-style file with coordinates for d5ieza2.
(The format of our PDB-style files is described here.)

Timeline for d5ieza2:

  • d5ieza2 appears in periodic updates to SCOPe 2.06 starting on 2017-01-19