SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5cird_ (5cir D:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2041369Fold b.22: TNF-like [49841] (1 superfamily)
    sandwich, 10 strands in 2 sheets; jelly-roll
  4. 2041370Superfamily b.22.1: TNF-like [49842] (2 families) (S)
  5. 2041371Family b.22.1.1: TNF-like [49843] (15 protein domains)
  6. 2041626Protein automated matches [190204] (3 species)
    not a true protein
  7. 2041627Species Human (Homo sapiens) [TaxId:9606] [186956] (10 PDB entries)
  8. 2285249Domain d5cird_: 5cir D: [328550]
    automated match to d1d4vb_
    complexed with cl, zn

Details for d5cird_

PDB Entry: 5cir (more details), 3 Å

PDB Description: crystal structure of death receptor 4 (dr4; tnffrsf10a) bound to trail (tnfsf10)
PDB Compounds: (D:) Tumor necrosis factor ligand superfamily member 10

SCOPe Domain Sequences for d5cird_:

Sequence, based on SEQRES records: (download)

>d5cird_ b.22.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pqrvaahitgtrgrsntlsspnsknekalgrkinswessrsghsflsnlhlrngelvihe
kgfyyiysqtyfrfqeeikentkndkqmvqyiykytsypdpillmksarnscwskdaeyg
lysiyqggifelkendrifvsvtnehlidmdheasffgaflvg

Sequence, based on observed residues (ATOM records): (download)

>d5cird_ b.22.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pqrvaahitgtrekalgrkinswessrsghsflsnlhlrngelvihekgfyyiysqtyfr
fqeeikentkndkqmvqyiykytsypdpillmksarnscwskdaeyglysiyqggifelk
endrifvsvtnehlidmdheasffgaflvg

SCOPe Domain Coordinates for d5cird_:

Click to download the PDB-style file with coordinates for d5cird_.
(The format of our PDB-style files is described here.)

Timeline for d5cird_:

  • d5cird_ appears in periodic updates to SCOPe 2.06 starting on 2017-01-19