SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5iezd2 (5iez D:171-171)

  1. Root: SCOPe 2.06
  2. 2245868Class l: Artifacts [310555] (1 fold)
  3. 2245869Fold l.1: Tags [310573] (1 superfamily)
  4. 2245870Superfamily l.1.1: Tags [310607] (1 family) (S)
  5. 2245871Family l.1.1.1: Tags [310682] (2 protein domains)
  6. 2251949Protein N-terminal Tags [310894] (1 species)
  7. 2251950Species Synthetic [311501] (10277 PDB entries)
  8. 2285217Domain d5iezd2: 5iez D:171-171 [328518]
    Other proteins in same PDB: d5ieza1, d5iezb_, d5iezc_, d5iezd1
    complexed with 6al

Details for d5iezd2

PDB Entry: 5iez (more details), 2.6 Å

PDB Description: discovery of potent myeloid cell leukemia-1 (mcl-1) inhibitors using structure-based design
PDB Compounds: (D:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d5iezd2:

Sequence; same for both SEQRES and ATOM records: (download)

>d5iezd2 l.1.1.1 (D:171-171) N-terminal Tags {Synthetic}

SCOPe Domain Coordinates for d5iezd2:

Click to download the PDB-style file with coordinates for d5iezd2.
(The format of our PDB-style files is described here.)

Timeline for d5iezd2:

  • d5iezd2 appears in periodic updates to SCOPe 2.06 starting on 2017-01-19