Lineage for d5tkdb_ (5tkd B:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2199100Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2199101Protein automated matches [190417] (25 species)
    not a true protein
  7. 2199241Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)
  8. 2284459Domain d5tkdb_: 5tkd B: [327760]
    automated match to d4l00b_
    complexed with 7gl, so4

Details for d5tkdb_

PDB Entry: 5tkd (more details), 1.92 Å

PDB Description: crystal structure of tyrosine kinase 2 jh2 (pseudo kinase domain) complexed with 6-[(3,5-dimethylphe nyl)amino]-8- (methylamino) imidazo[1,2-b]pyridazine-3-carbo xamide
PDB Compounds: (B:) Non-receptor tyrosine-protein kinase TYK2

SCOPe Domain Sequences for d5tkdb_:

Sequence, based on SEQRES records: (download)

>d5tkdb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fhrvdqkeitqlshlgqgtrtnvyegrlrvegsgdpeegkmddedplvpgrdrgqelrvv
lkvldpshhdialafyetaslmsqvshthlafvhgvcvrgpenimvteyvehgpldvwlr
rerghvpmawkmvvaqqlasalsylenknlvhgnvcgrnillarlglaegtspfiklsdp
gvglgalsreerveripwlapeclpgganslstamdkwgfgatlleicfdgeaplqsrsp
sekehfyqrqhrlpepscpqlatltsqcltyeptqrpsfrtilrdlt

Sequence, based on observed residues (ATOM records): (download)

>d5tkdb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fhrvdqkeitqlshlgqgtrtnvyegrlrelrvvlkvldpshhdialafyetaslmsqvs
hthlafvhgvcvrgpenimvteyvehgpldvwlrrerghvpmawkmvvaqqlasalsyle
nknlvhgnvcgrnillarlglaspfiklsdpgvglgalsreerveripwlapeclpstam
dkwgfgatlleicfdgeaplrspsekehfyqrqhrlpepslatltsqcltyeptqrpsfr
tilrdlt

SCOPe Domain Coordinates for d5tkdb_:

Click to download the PDB-style file with coordinates for d5tkdb_.
(The format of our PDB-style files is described here.)

Timeline for d5tkdb_:

  • d5tkdb_ appears in periodic updates to SCOPe 2.06 starting on 2016-12-30