SCOPe 2.06: Domain d5fm3a_: 5fm3 A:

Lineage for d5fm3a_ (5fm3 A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d5fm3a_: 5fm3 A: [327565]
   automated match to d4j98a_
   complexed with pp1

Details for d5fm3a_

PDB Entry: 5fm3, 2.95 Å

PDB Description: crystal structure of hyper-phosphorylated ret kinase domain with (proximal) juxtamembrane segment

PDB Compounds: (A:) proto-oncogene tyrosine-protein kinase receptor ret

SCOPe Domain Sequences for d5fm3a_:

Sequence, based on SEQRES records:

>d5fm3a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dafkiledpkwefprknlvlgktlgegefgkvvkatafhlkgragyttvavkmlkenasp
selrdllsefnvlkqvnhphviklygacsqdgpllliveyakygslrgflresrkvgpgy
lgsggsrnsssldhpderaltmgdlisfawqisqgmqylaemklvhrdlaarnilvaegr
kmkisdfglsrdvyeedsyvkrsqgripvkwmaieslfdhiyttqsdvwsfgvllweivt
lggnpypgipperlfnllktghrmerpdncseemyrlmlqcwkqepdkrpvfadiskdle
kmmvk

Sequence, based on observed residues (ATOM records):

>d5fm3a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dafkiledpkwefprknlvlgktlgegefgkvvkatafhlkgragyttvavkmlkenasp
selrdllsefnvlkqvnhphviklygacsqdgpllliveyakygslrgflresaltmgdl
isfawqisqgmqylaemklvhrdlaarnilvaegrkmkisdfglsrdvyeedsyvkrsqg
ripvkwmaieslfdhiyttqsdvwsfgvllweivtlggnpypgipperlfnllktghrme
rpdncseemyrlmlqcwkqepdkrpvfadiskdlekmmvk

Timeline for d5fm3a_:

• d5fm3a_ is new in SCOPe 2.06-stable
  
• d5fm3a_ appears in SCOPe 2.07
  
• d5fm3a_ appears in the current release, SCOPe 2.08