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Lineage for d5thtc_ (5tht C:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2115321Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
    3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456
  4. 2115322Superfamily c.42.1: Arginase/deacetylase [52768] (3 families) (S)
  5. 2115600Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 protein domains)
    automatically mapped to Pfam PF00850
  6. 2115643Protein automated matches [190786] (1 species)
    not a true protein
  7. 2115644Species Human (Homo sapiens) [TaxId:9606] [188039] (32 PDB entries)
  8. 2284243Domain d5thtc_: 5tht C: [327544]
    Other proteins in same PDB: d5thta2, d5thtb2
    automated match to d2v5wb_
    complexed with b3n, edo, k, zn

Details for d5thtc_

PDB Entry: 5tht (more details), 2.41 Å

PDB Description: crystal structure of g303a hdac8 in complex with m344
PDB Compounds: (C:) Histone deacetylase 8

SCOPe Domain Sequences for d5thtc_:

Sequence, based on SEQRES records: (download)

>d5thtc_ c.42.1.2 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegdddhpdsieyglgydcpategifdyaaaiggatitaaqclidgmckv
ainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsfts
kvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyq
afnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilgaggynlantar
cwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnl
khvv

Sequence, based on observed residues (ATOM records): (download)

>d5thtc_ c.42.1.2 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqeeygldcpategifdyaaaiggatitaaqclidgmckvainwsggwhha
kkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvslhkfs
pgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkavvlql
gadtiagdpmcsfnmtpvgigkclkyilqwqlatlilgaggynlantarcwtyltgvilg
ktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlkhvv

SCOPe Domain Coordinates for d5thtc_:

Click to download the PDB-style file with coordinates for d5thtc_.
(The format of our PDB-style files is described here.)

Timeline for d5thtc_:

  • d5thtc_ appears in periodic updates to SCOPe 2.06 starting on 2016-12-22