SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5ttfb_ (5ttf B:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2072411Fold b.85: beta-clip [51268] (7 superfamilies)
    double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll
  4. 2073020Superfamily b.85.7: SET domain [82199] (4 families) (S)
    duplication: the core is composed of two structural repeats similar to (circularly permuted) repeats of AFPIII
    also contains a substrate-binding alpha+beta subdomain inserted in the core
  5. 2073097Family b.85.7.0: automated matches [227191] (1 protein)
    not a true family
  6. 2073098Protein automated matches [226914] (1 species)
    not a true protein
  7. 2073099Species Human (Homo sapiens) [TaxId:9606] [225158] (17 PDB entries)
  8. 2284234Domain d5ttfb_: 5ttf B: [327535]
    automated match to d3k5ka_
    complexed with 7kz, cl, sam, unx, zn

Details for d5ttfb_

PDB Entry: 5ttf (more details), 1.72 Å

PDB Description: crystal structure of catalytic domain of g9a with ms012
PDB Compounds: (B:) Histone-lysine N-methyltransferase EHMT2

SCOPe Domain Sequences for d5ttfb_:

Sequence, based on SEQRES records: (download)

>d5ttfb_ b.85.7.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tekiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnithlqhctcv
ddcsssnclcgqlsircwydkdgrllqefnkiepplifecnqacscwrncknrvvqsgik
vrlqlyrtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdldnkdgevy
cidaryygnisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeelgfdygdr
fwdikskyftcqcgsekckhsaeaialeqsr

Sequence, based on observed residues (ATOM records): (download)

>d5ttfb_ b.85.7.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tekiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnithlqhctcv
ddcsssnclcgqlsircwydkdgrllqefnkiepplifecnqacscwrncknrvvqsgik
vrlqlyrtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdldnevycid
aryygnisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeelgfdygdrfwd
ikskyftcqcgsekckhsaeaialeqsr

SCOPe Domain Coordinates for d5ttfb_:

Click to download the PDB-style file with coordinates for d5ttfb_.
(The format of our PDB-style files is described here.)

Timeline for d5ttfb_:

  • d5ttfb_ appears in periodic updates to SCOPe 2.06 starting on 2016-12-22